RADICAL HOLISM IN THE MANAGEMENT OF ANXIETY AND DEPRESSION

RADICAL HOLISM IN THE MANAGEMENT OF ANXIETY AND DEPRESSION

30.00

KELLY BROGAN, MD

The monoamine hypotheses about psychiatry and associated treatments have revealed their limitations, and it is time to explore what the literature has been supporting for two decades:  the inflammatory model of mental illness and the relevance of psychoneuroimmunology to a systems-based approach in the treatment of patients with syndromal depression. The role of cytokines and the immune system in depression is well-established as is the relationship between gut microbiota, intestinal integrity, and the brain. Exploring the gut-immune-brain connection, we must also consider the mediating role of the endocrine system. Lifestyle interventions around gut, immune, and anti-inflammatory influences will be explored, as will epigenetic modulators such as probiotics, methyl donors, and therapeutic foods.

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